Elevated serum creatinine which means 50% of kidney function has been lost

Does Creatinine 1.6 Means Kidney Function is Just Remaining 50% ,Glomerular compensatory same reason, the body also has a strong compensatory renal function. Human kidney is composed of about two sisters, under normal circumstances, there is a sister to work properly, it is sufficient to meet the daily needs of the body. Therefore, some patients with renal failure acceptable relatives donated kidneys to get a new life, but also as usual living relatives to donate a kidney, serum creatinine test his completely normal. In general, patients with renal function has been damaged by more than 50% -70%, will be reflected in the serum creatinine values. In other words, once elevated serum creatinine, renal function may have lost more than 50%.

What led to this 50% of kidney function loss? This is inextricably linked with the above-mentioned glomerulosclerosis. Due to a variety of pathogenic factors leading to the occurrence of renal inflammatory response, inflammatory reaction will release inflammatory factors and renal toxicity factor, glomerular sclerosis in damage occurred in the course of long-term, at the same time, between tubules, interstitial will suffer damage, renal tubular - interstitial fibrosis, causing a large area of the entire kidney tissue fibrosis, eventually scar (ie hardening). Glomerulosclerosis process, glomerular can work less and less, but growing share of the workload, toxic substances within the kidney is still on them, "attack", the workload of this overload will one day remaining glomeruli overwhelmed, lost the ability to filter creatinine no place to be discharged, but to remain in the blood, so blood tests in elevated creatinine.

Seen, when elevated serum creatinine, renal function has already been damaged, so the judge renal function of various factors to be considered in order to make a comprehensive and objective evaluation.

Considering serum creatinine, and other various factors:

Now often used to estimate glomerular filtration rate or creatinine clearance rate used by the US National Kidney Foundation recommends the formula method clinically. These formulas are based on past experience accumulated in clinical practice, considering the influence of serum creatinine, age, gender, race, weight, etc., and thus is now generally considered to be more accurate and reasonable than serum creatinine alone.