PKD Treatment is generally diagnosed through a urinalysis

PKD Treatment is generally diagnosed through a urinalysis and a blood chemistry panel. There are many causes of kidney failure, however. To determine if the affected cat has Polycystic kidney disease, an ultrasound examination is generally performed. On palpation, the kidneys may feel enlarged and irregular in shape. DNA testing is available to determine which cats may be at risk for polycystic kidney disease.

Given the data we have so far, it appears that octreotide could have a potential role in the treatment of PKD. For some reason, it appears that octreotide slows growth in kidney volume over one year, but the effects become insignificant over the long term.

Obviously, more comprehensive studies looking at long-term hard outcome data are needed. Another interesting thing would be to compare the data for octreotide vs. tolvaptan. Although both these agents have shown promise so far (in addition to other contenders like mTOR inhibitors), a major concern is cost. All other things being equal, octreotide could me a cheaper alternative than tolvaptan for what essentially could be a lifelong treatment


Because there is no cure for polycystic kidney disease, treatment options for the disease focus on treating its symptoms and complications, while improving the quality of life. A few treatment methods include medicine, surgery, dialysis, and kidney transplantation. Keeping blood pressure under control through diet changes can also be important for a person with polycystic kidney disease.

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