Anemia in kidney disease how to treat it

CKD Treatment

Anemia in kidney disease how to treat it 
Chronic renal failure patients under normal circumstances would appear that common symptoms of renal anemia. Under normal circumstances, our kidneys secrete pro red blood cells (rbc) erythropoietin function, however, impaired renal function to stage chronic renal failure, the kidneys produce erythropoietin deficiency or some uremic plasma toxic substances interfering red blood cells (rbc) generation and metabolism, it will lead to renal anemia. So, chronic renal failure renal anemia how to treat it?

Treatment of anemia in chronic kidney disease, renal medicine are the following:

1. androgens: In clinical practice, for the treatment of chronic kidney disease, many of which are using hormone therapy, such as testosterone propionate, 50mg intramuscularly daily or every other day, or a derivative of testosterone hydroxymethyl fluoride, daily 10 ~ 30mg orally. Or Nandrolone 25 ~ 50mg, 2 times a week, intramuscular injection. After improving renal anemia, can be applied to maintain the amount of intramuscular injection every two weeks or monthly testosterone propionate 100mg.

2. cobalt chloride, in addition to the above, cobalt chloride, the drug every 20 ~ 50mg, 2 to 3 times a day, orally. Gastrointestinal reactions taking cobalt chloride, can be applied enteric-coated capsules or add services to protect drug.

3. We all know that the treatment of chronic kidney disease is very important, especially recombinant human red blood cells and promote (rbc) erythropoietin (rhuepo): rhuepo is a glycoprotein hormone, the site of action in the bone marrow to make blood early development red blood cells (rbc) increase the number and improve renal anemia, the effective rate of 90%, hemoglobin can be increased to 100g / l or more.

4. Other drugs: for lack of essential amino acids, essential amino acids should be given treatment. Because vitamin b6, vitamin b12, folic acid, ascorbic acid deficiency, may be appropriate to add. If chronic blood loss, iron supplements should be.

5. transfusion: Anemia is one of the common symptoms of chronic kidney disease and uremia, general uremic patients with renal anemia tolerance is very strong, but also the risk of excessive blood transfusion, it is only hemoglobin 70g / l or less, have kidney anemia, heart failure, angina, or gastrointestinal and intracerebral hemorrhage were given blood transfusions, the best selection of freshly prepared blood red blood cell concentrate (rbc). Every blood transfusion should not be excessive, excessive red blood cell transfusion inhibit pro (rbc) LH secretion, the red blood cells (rbc) decreased production.